Kinesin-2 Controls the Motility of RAB5 Endosomes and Their Association with the Spindle in Mitosis

Kinesin-2 Controls the Motility of RAB5 Endosomes and Their Association with the Spindle in Mitosis

RAB5 is a small GTPase that belongs to the wide family of Rab proteins and localizes on early endosomes. In its active GTP-bound form, RAB5 recruits downstream effectors that, in turn, are responsible for distinct aspects of early endosome function, including their movement along microtubules. We pr...

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Bibliographic Details
Main Authors: Emanuela Pupo, Daniele Avanzato, Marco Scianna, Amanda Oldani, Guido Serini, Letizia Lanzetti
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:International Journal of Molecular Sciences
Subjects:
RAB5
Kinesin-2
KIF3A
KIF3B
mitosis
nuclear envelope breakdown
vesicular trafficking
Online Access:http://www.mdpi.com/1422-0067/19/9/2575

Internet

http://www.mdpi.com/1422-0067/19/9/2575

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