Inhibitory Effects of Menadione on Helicobacter pylori Growth and Helicobacter pylori-Induced Inflammation via NF-κB Inhibition

Inhibitory Effects of Menadione on Helicobacter pylori Growth and Helicobacter pylori-Induced Inflammation via NF-κB Inhibition

H. pylori is classified as a group I carcinogen by WHO because of its involvement in gastric cancer development. Several reports have suggested anti-bacterial effects of menadione, although the effect of menadione on major virulence factors of H. pylori and H. pylori-induced inflammation is yet to b...

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Bibliographic Details
Main Authors: Min Ho Lee, Ji Yeong Yang, Yoonjung Cho, Hyun Jun Woo, Hye Jin Kwon, Do Hyun Kim, Min Park, Cheol Moon, Min Ji Yeon, Hyun Woo Kim, Woo-Duck Seo, Sa-Hyun Kim, Jong-Bae Kim
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
H. pylori
menadione
CagA
VacA
T4SS
inflammation
NF-κB
IL-8
Online Access:http://www.mdpi.com/1422-0067/20/5/1169

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http://www.mdpi.com/1422-0067/20/5/1169

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