Hypermethylation of the TPEF/HPP1 Gene in Primary, Metastatic Colorectal Cancers

The role of promoter methylation in the process of cancer cell metastasis has not yet been studied. Recently, methylation of the TPEF (transmembrane protein containing epidermal growth factor, follistatin domain) gene was reported in human colon, gastric, bladder cancer cells. Using the Methylight...

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Bibliographic Details
Main Authors: Matthias P.A. Ebert, Suzanne H. Mooney, Lori Tonnes-Priddy, Joe Lograsso, Juliane Hoffmann, Jie Chent, Christoph Rocken, Hans-Ulrich Schulz, Peter Malfertheiner, Catherine Lofton-Day
Format: Article
Language:English
Published: Elsevier 2005-08-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558605801095