Dihydroartemisinin Alleviates Imiquimod-Induced Psoriasis-like Skin Lesion in Mice Involving Modulation of IL-23/Th17 Axis

Dihydroartemisinin Alleviates Imiquimod-Induced Psoriasis-like Skin Lesion in Mice Involving Modulation of IL-23/Th17 Axis

Background: Psoriasis is a T help 17 (Th17) cell-mediated chronic inflammatory skin disease. Recent studies have shown that dihydroartemisinin (DHA) can significantly reduce experimental autoimmune encephalomyelitis and rheumatoid arthritis by regulating Th17 cells.Objective: To verify whether DHA c...

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Bibliographic Details
Main Authors: Jiang-Min Liu, Quan-Xin Jin, Manabu Fujimoto, Fang-Fang Li, Lin-Bo Jin, Ran Yu, Guang-Hai Yan, Lian-Hua Zhu, Fan-Ping Meng, Qing-Gao Zhang, Gui-Hua Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Pharmacology
Subjects:
dihydroartemisinin
psoriasis
Il-23/th17 axis
cytokines
T cells
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.704481/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.704481/full

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