RND multidrug efflux-pumps: what are they good for?

Multidrug efflux pumps are chromosomally encoded genetic elements capable of mediating resistance to toxic compounds in several life forms. In bacteria, these elements are involved in intrinsic and acquired resistance to antibiotics. Unlike other well-known horizontally acquired antibiotic resistanc...

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Bibliographic Details
Main Authors: Carolina eAlvarez-Ortega, Jorge eOlivares, Jose L Martinez
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-02-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00007/full