Identifying the limits for ellagic acid bioavailability: A crossover pharmacokinetic study in healthy volunteers after consumption of pomegranate extracts

Ellagic acid (EA) is a polyphenol that must be released from the non-bioavailable ellagitannins in pomegranates, walnuts or strawberries to be absorbed. To estimate whether EA bioavailability could be improved after consumption of a high free EA amount, we conducted a crossover pharmacokinetic study...

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Bibliographic Details
Main Authors: Antonio González-Sarrías, Rocío García-Villalba, M. Ángeles Núñez-Sánchez, Joao Tomé-Carneiro, Pilar Zafrilla, Juana Mulero, Francisco A. Tomás-Barberán, Juan Carlos Espín
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464615004363