Negative Cellular Effects of Urban Particulate Matter on Human Keratinocytes Are Mediated by P38 MAPK and NF-κB-dependent Expression of TRPV 1

Negative Cellular Effects of Urban Particulate Matter on Human Keratinocytes Are Mediated by P38 MAPK and NF-κB-dependent Expression of TRPV 1

Urban particulate matter (UPM) exerts negative effects on various human organs. Transient receptor potential vanilloid 1 (TRPV1) is a polymodal sensory transducer that can be activated by multiple noxious stimuli. This study aimed to explore the effects of the UPM 1648a on the expression of TRPV1, a...

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Bibliographic Details
Main Authors: Kitae Kwon, See-Hyoung Park, Byung Seok Han, Sae Woong Oh, Seung Eun Lee, Ju Ah Yoo, Se Jung Park, Jangsoon Kim, Ji Woong Kim, Jae Youl Cho, Jongsung Lee
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
human keratinocytes
TRPV 1
MAPK
NF-κB
UPM
skin
Online Access:http://www.mdpi.com/1422-0067/19/9/2660

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