Amlodipine Ameliorates Up-Regulation of ET-1 in Left Ventricle of Hypercholesterolemia Rabbits

Objective(s)In addition to antihypertensive effects, amlodipine may exhibit cardiovascular protective effects in heart tissue. The aim of this study was to evaluate the effects of amlodipine and/or high cholesterol diet on blood, heart tissue concentration and mRNA expression of endothelin-1 (ET-1)...

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Bibliographic Details
Main Authors: Iraj Salehi, Safar Farajnia, Mustafa Mohammadi, Masoud Sabouri Ghannad
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2010-09-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://www.mums.ac.ir/shares/basic_medical/basicmedjou/89/fall/a11.pdf