Engineering Cellular Biosensors with Customizable Antiviral Responses Targeting Hepatitis B Virus

Engineering Cellular Biosensors with Customizable Antiviral Responses Targeting Hepatitis B Virus

Summary: SynNotch receptor technology is a versatile tool that uses the regulatory notch core portion with an extracellular scFv and an intracellular transcription factor that enables to program customized input and output functions in mammalian cells. In this study, we designed a novel synNotch rec...

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Bibliographic Details
Main Authors: Satoko Matsunaga, Sundararaj S. Jeremiah, Kei Miyakawa, Daisuke Kurotaki, Sayaka Shizukuishi, Koichi Watashi, Hironori Nishitsuji, Hirokazu Kimura, Tomohiko Tamura, Naoki Yamamoto, Kunitada Shimotohno, Takaji Wakita, Akihide Ryo
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422030050X

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http://www.sciencedirect.com/science/article/pii/S258900422030050X

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