<i>Nigella sativa</i> and Thymoquinone: A Natural Blessing for Periodontal Therapy
Thymoquinone<i> </i>(TQ), the chief active constituent of Nigella sativa (NS)<i>,</i> shows very valuable biomedical properties such as antioxidant, antimicrobial, anticancer, anti-inflammatory, antihypertensive, hypoglycemic, antiparasitic and anti-asthmatic effects. Several...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-12-01
|
Series: | Antioxidants |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3921/9/12/1260 |
id |
doaj-bd9128d6c6c443f9bc8f6ca07c5012a3 |
---|---|
record_format |
Article |
spelling |
doaj-bd9128d6c6c443f9bc8f6ca07c5012a32020-12-12T00:06:20ZengMDPI AGAntioxidants2076-39212020-12-0191260126010.3390/antiox9121260<i>Nigella sativa</i> and Thymoquinone: A Natural Blessing for Periodontal TherapyMohamed Mekhemar0Yasmine Hassan1Christof Dörfer2Clinic for Conservative Dentistry and Periodontology, School of Dental Medicine, Christian-Albrecht’s University, 24105 Kiel, GermanyClinic for Conservative Dentistry and Periodontology, School of Dental Medicine, Christian-Albrecht’s University, 24105 Kiel, GermanyClinic for Conservative Dentistry and Periodontology, School of Dental Medicine, Christian-Albrecht’s University, 24105 Kiel, GermanyThymoquinone<i> </i>(TQ), the chief active constituent of Nigella sativa (NS)<i>,</i> shows very valuable biomedical properties such as antioxidant, antimicrobial, anticancer, anti-inflammatory, antihypertensive, hypoglycemic, antiparasitic and anti-asthmatic effects. Several studies have examined the pharmacological actions of TQ in the treatment of oral diseases but its potential role in periodontal therapy and regeneration is not yet fully defined. The present investigation has been designed to review the scientific studies about the effects of TQ as an adjunct to periodontal treatment to promote healing and periodontal regeneration. Along with clinical experiments, in vitro studies exhibit the beneficial effects of TQ during periodontal therapy. Nevertheless, additional comprehensive clinical and preclinical studies at cellular and molecular levels are essential to examine the particular action mechanisms of Nigella sativa and its elements, particularly TQ, during periodontal treatment or regeneration.https://www.mdpi.com/2076-3921/9/12/1260thymoquinone<i>Nigella sativa</i>periodontal diseaseperiodontitisanti-inflammatoriesantioxidants |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mohamed Mekhemar Yasmine Hassan Christof Dörfer |
spellingShingle |
Mohamed Mekhemar Yasmine Hassan Christof Dörfer <i>Nigella sativa</i> and Thymoquinone: A Natural Blessing for Periodontal Therapy Antioxidants thymoquinone <i>Nigella sativa</i> periodontal disease periodontitis anti-inflammatories antioxidants |
author_facet |
Mohamed Mekhemar Yasmine Hassan Christof Dörfer |
author_sort |
Mohamed Mekhemar |
title |
<i>Nigella sativa</i> and Thymoquinone: A Natural Blessing for Periodontal Therapy |
title_short |
<i>Nigella sativa</i> and Thymoquinone: A Natural Blessing for Periodontal Therapy |
title_full |
<i>Nigella sativa</i> and Thymoquinone: A Natural Blessing for Periodontal Therapy |
title_fullStr |
<i>Nigella sativa</i> and Thymoquinone: A Natural Blessing for Periodontal Therapy |
title_full_unstemmed |
<i>Nigella sativa</i> and Thymoquinone: A Natural Blessing for Periodontal Therapy |
title_sort |
<i>nigella sativa</i> and thymoquinone: a natural blessing for periodontal therapy |
publisher |
MDPI AG |
series |
Antioxidants |
issn |
2076-3921 |
publishDate |
2020-12-01 |
description |
Thymoquinone<i> </i>(TQ), the chief active constituent of Nigella sativa (NS)<i>,</i> shows very valuable biomedical properties such as antioxidant, antimicrobial, anticancer, anti-inflammatory, antihypertensive, hypoglycemic, antiparasitic and anti-asthmatic effects. Several studies have examined the pharmacological actions of TQ in the treatment of oral diseases but its potential role in periodontal therapy and regeneration is not yet fully defined. The present investigation has been designed to review the scientific studies about the effects of TQ as an adjunct to periodontal treatment to promote healing and periodontal regeneration. Along with clinical experiments, in vitro studies exhibit the beneficial effects of TQ during periodontal therapy. Nevertheless, additional comprehensive clinical and preclinical studies at cellular and molecular levels are essential to examine the particular action mechanisms of Nigella sativa and its elements, particularly TQ, during periodontal treatment or regeneration. |
topic |
thymoquinone <i>Nigella sativa</i> periodontal disease periodontitis anti-inflammatories antioxidants |
url |
https://www.mdpi.com/2076-3921/9/12/1260 |
work_keys_str_mv |
AT mohamedmekhemar inigellasativaiandthymoquinoneanaturalblessingforperiodontaltherapy AT yasminehassan inigellasativaiandthymoquinoneanaturalblessingforperiodontaltherapy AT christofdorfer inigellasativaiandthymoquinoneanaturalblessingforperiodontaltherapy |
_version_ |
1724385927233536000 |