Chlamydia muridarum lung infection in infants alters hematopoietic cells to promote allergic airway disease in mice.

BACKGROUND: Viral and bacterial respiratory tract infections in early-life are linked to the development of allergic airway inflammation and asthma. However, the mechanisms involved are not well understood. We have previously shown that neonatal and infant, but not adult, chlamydial lung infections...

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Main Authors: Malcolm R Starkey, Richard Y Kim, Emma L Beckett, Heidi C Schilter, Doris Shim, Ama-Tawiah Essilfie, Duc H Nguyen, Kenneth W Beagley, Joerg Mattes, Charles R Mackay, Jay C Horvat, Philip M Hansbro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3411632?pdf=render