Folic Acid Induces Intake-Related Changes in the Mammary Tissue Transcriptome of C57BL/6 Mice

Folic Acid Induces Intake-Related Changes in the Mammary Tissue Transcriptome of C57BL/6 Mice

Folic acid (FA) intake has been associated with increased breast cancer risk in some studies. Although underlying mechanisms are unknown, epigenetic modifications that persistently alter transcription have been suggested. We tested the hypothesis that high FA (HFA) intake alters the adult mammary tr...

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Bibliographic Details
Main Authors: Mark A. Burton, Elie Antoun, Reyna S. Penailillo, Graham C. Burdge, Karen A. Lillycrop
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Nutrients
Subjects:
folic acid
mammary gland
transcriptome
breast cancer
EZH2
Online Access:https://www.mdpi.com/2072-6643/12/9/2821

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