A method to assess linkage disequilibrium between CNVs and SNPs inside copy number variable regions

Since the discovery of the ubiquitous contribution of copy number variation to genetic variability, researchers have commonly used metrics such as r-squared to quantify linkage disequilibrium (LD) between copy number variants (CNVs) and single nucleotide polymorphisms (SNPs). However, these reports...

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Bibliographic Details
Main Authors: Nathan E Wineinger, Nicholas M Pajewski, Hemant K Tiwari
Format: Article
Published: Frontiers Media S.A. 2011-04-01
Series:Frontiers in Genetics
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2011.00017/full