Neuronal Activity-Dependent Activation of Astroglial Calcineurin in Mouse Primary Hippocampal Cultures

Neuronal Activity-Dependent Activation of Astroglial Calcineurin in Mouse Primary Hippocampal Cultures

Astrocytes respond to neuronal activity by generating calcium signals which are implicated in the regulation of astroglial housekeeping functions and/or in modulation of synaptic transmission. We hypothesized that activity-induced calcium signals in astrocytes may activate calcineurin (CaN), a calci...

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Bibliographic Details
Main Authors: Dmitry Lim, Lisa Mapelli, Pier Luigi Canonico, Francesco Moccia, Armando A. Genazzani
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
astrocytes
calcineurin
neuronal activity
NMDA
mGluR5
store-operated calcium entry
Online Access:http://www.mdpi.com/1422-0067/19/10/2997

Internet

http://www.mdpi.com/1422-0067/19/10/2997

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