Transcriptional Modulation of the Hippo Signaling Pathway by Drugs Used to Treat Bipolar Disorder and Schizophrenia

Transcriptional Modulation of the Hippo Signaling Pathway by Drugs Used to Treat Bipolar Disorder and Schizophrenia

Recent reports suggest a link between positive regulation of the Hippo pathway with bipolar disorder (BD), and the Hippo pathway is known to interact with multiple other signaling pathways previously associated with BD and other psychiatric disorders. In this study, neuronal-like NT2 cells were trea...

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Bibliographic Details
Main Authors: Bruna Panizzutti, Chiara C. Bortolasci, Briana Spolding, Srisaiyini Kidnapillai, Timothy Connor, Mark F. Richardson, Trang T. T. Truong, Zoe S. J. Liu, Gerwyn Morris, Laura Gray, Jee Hyun Kim, Olivia M. Dean, Michael Berk, Ken Walder
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
Hippo pathway
psychotropic drugs
bipolar disorder
schizophrenia
inflammation
drug repurposing
Online Access:https://www.mdpi.com/1422-0067/22/13/7164

Internet

https://www.mdpi.com/1422-0067/22/13/7164

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