Dietary Copper Reduces the Hepatotoxicity of (−)-Epigallocatechin-3-Gallate in Mice

We developed Cu-deficient, -sufficient and -super nutrition mice models by feeding them with diet containing 1.68, 11.72 or 51.69 mg of Cu/kg for 28 days, respectively. Then, the mice were treated to (−)-epigallocatechin-3-gallate (EGCG, 750 mg/kg BW) by oral in order to assess the acute toxicity of...

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Bibliographic Details
Main Authors: Najeeb Ahmed Kaleri, Kang Sun, Le Wang, Jin Li, Wenzheng Zhang, Xuan Chen, Xinghui Li
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Molecules
Subjects:
tea
Online Access:https://www.mdpi.com/1420-3049/23/1/38