Inhibition of Glutathione Synthesis via Decreased Glucose Metabolism in Stored RBCs

Inhibition of Glutathione Synthesis via Decreased Glucose Metabolism in Stored RBCs

Background/Aims: Although red blood cells (RBCs) transfusions can be lifesaving, they are not without risk. RBCs storage is associated with the abnormal metabolism of glutathione (GSH), which may increase the risk of the oxidative damage of RBCs after transfusion. The responsible mechanisms remain u...

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Bibliographic Details
Main Authors: Yanlian Xiong, Yanlei Xiong, Yueming Wang, Zhuoya Wang, Aiping Zhang, Nannan Zhao, Dongmei Zhao, Zhenhai Yu, Zhiqiang Wang, Junzhu Yi, Xiying Luan
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Blood storage
Oxidative Damage
RBCs
Glutathione
Online Access:https://www.karger.com/Article/FullText/495864

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https://www.karger.com/Article/FullText/495864

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