The Bone Buttress Theory: The Effect of the Mechanical Loading of Bone on the Osseointegration of Dental Implants

• Main Authors: David Chavarri-Prado, Aritza Brizuela-Velasco, Ángel Álvarez-Arenal, Markel Dieguez-Pereira, Esteban Pérez-Pevida, Iratxe Viteri-Agustín, Alejandro Estrada-Martínez
• Format: Article
• Language: English
• Published: MDPI AG 2021-12-01
• Series: Biology
• Subjects: implant stability; resonance frequency analysis; osseointegration; immediate loading; BIC
• Online Access: https://www.mdpi.com/2079-7737/10/1/12

Objectives: To determine the effect of mechanical loading of bone on the stability and histomorphometric variables of the osseointegration of dental implants using an experimental test in an animal model. Materials and Methods: A total of 4 human implants were placed in both tibiae of 10 New Zealand rabbits (<i>n</i> = 40). A 6-week osseointegration was considered, and the rabbits were randomly assigned to two groups: Group A (Test group) included 5 rabbits that ran on a treadmill for 20 min daily during the osseointegration period; Group B (Controls) included the other 5 that were housed conventionally. The monitored variables were related to the primary and secondary stability of the dental implants (implant stability quotient—ISQ), vertical bone growth, bone to implant contact (BIC), area of regenerated bone and the percentage of immature matrix. Results: The results of the study show a greater vertical bone growth (Group A 1.26 ± 0.48 mm, Group B 0.32 ± 0.47 mm, <i>p</i> < 0.001), higher ISQ values (Group A 11.25 ± 6.10 ISQ, 15.73%; Group B 5.80 ± 5.97 ISQ, 7.99%, <i>p</i> = 0.006) and a higher BIC (Group A 19.37%, Group B 23.60%, <i>p</i> = 0.0058) for implants in the test group, with statistically significant differences. A higher percentage of immature bone matrix was observed for implants in the control group (20.68 ± 9.53) than those in the test group (15.38 ± 8.84) (<i>p</i> = 0.108). A larger area of regenerated bone was also observed for the test implants (Group A 280.50 ± 125.40 mm², Group B 228.00 ± 141.40 mm²), but it was not statistically significant (<i>p</i> = 0.121). Conclusions: The mechanical loading of bone improves the stability and the histomorphometric variables of the osseointegration of dental implants.