Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death.

Vertebrate genomes undergo epigenetic reprogramming during development and disease. Emerging evidence suggests that DNA methylation plays a key role in cell fate determination in the retina. Despite extensive studies of the programmed cell death that occurs during retinal development and degeneratio...

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Bibliographic Details
Main Authors: Karl J Wahlin, Raymond A Enke, John A Fuller, Giedrius Kalesnykas, Donald J Zack, Shannath L Merbs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3823652?pdf=render