Inhibition of AZIN2-sv induces neovascularization and improves prognosis after myocardial infarction by blocking ubiquitin-dependent talin1 degradation and activating the Akt pathwayResearch in context

Inhibition of AZIN2-sv induces neovascularization and improves prognosis after myocardial infarction by blocking ubiquitin-dependent talin1 degradation and activating the Akt pathwayResearch in context

Background: We previously found that loss of lncRNA-AZIN2 splice variant (AZIN2-sv) increases cardiomyocyte (CM) proliferation and attenuates adverse ventricular remodelling post-myocardial infarction (MI). However, whether inhibition of AZIN2-sv can simultaneously induce angiogenesis and thus impro...

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Bibliographic Details
Main Authors: Xinzhong Li, Yili Sun, Senlin Huang, Yanmei Chen, Xiaoqiang Chen, Mengsha Li, Xiaoyun Si, Xiang He, Hao Zheng, Lintao Zhong, Yang Yang, Wangjun Liao, Yulin Liao, Guojun Chen, Jianping Bin
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418305723

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