Development of thermosensitive poloxamer 407-based microbubble gel with ultrasound mediation for inner ear drug delivery

Development of thermosensitive poloxamer 407-based microbubble gel with ultrasound mediation for inner ear drug delivery

Our previous study first investigated feasibility of applying ultrasound (US) and microbubbles (MBs) via external auditory canal to facilitate drug delivery into inner ear. However, most drugs are in aqueous formulae and eliminated via Eustachian tubes after drug application. In this study, feasibil...

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Bibliographic Details
Main Authors: Ai-Ho Liao, Cheng-Ping Shih, Ming-Wei Li, Yi-Chun Lin, Ho-Chiao Chuang, Chih-Hung Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Drug Delivery
Subjects:
ultrasound
microbubbles
cavitation
thermosensitive gel
poloxamer 407
dexamethasone
Online Access:http://dx.doi.org/10.1080/10717544.2021.1938758

Internet

http://dx.doi.org/10.1080/10717544.2021.1938758

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