Downregulation of serine protease HTRA1 is associated with poor survival in breast cancer.

HTRA1 is a highly conserved serine protease which has been implicated in suppression of epithelial-to-mesenchymal-transition (EMT) and cell motility in breast cancer. Its prognostic relevance for breast cancer is unclear so far. Therefore, we evaluated the impact of HTRA1 mRNA expression on patient...

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Bibliographic Details
Main Authors: Anna Lehner, Viktor Magdolen, Tibor Schuster, Matthias Kotzsch, Marion Kiechle, Alfons Meindl, Fred C G J Sweep, Paul N Span, Eva Gross
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23580433/?tool=EBI