Induction of ectopic retina-like tissue by transgenic expression of neurogenin.

Degeneration of retinal neurons is an underlying cause of several major types of blinding diseases, and effective therapies remain to be developed. The suppositive strategy of repopulating a degenerative retina with new cells generated onsite faces serious challenges, because the mammalian retina se...

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Bibliographic Details
Main Authors: Run-Tao Yan, Li He, Wenjie Zhan, Shu-Zhen Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4312083?pdf=render