Wnt5a through noncanonical Wnt/JNK or Wnt/PKC signaling contributes to the differentiation of mesenchymal stem cells into type II alveolar epithelial cells in vitro.

The differentiation of mesenchymal stem cells (MSCs) into type II alveolar epithelial (AT II) cells is critical for reepithelization and recovery in acute respiratory distress syndrome (ARDS), and Wnt signaling was considered to be the underlying mechanisms. In our previous study, we found that cano...

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Bibliographic Details
Main Authors: Airan Liu, Song Chen, Shixia Cai, Liang Dong, Le Liu, Yi Yang, Fengmei Guo, Xiaomin Lu, Hongli He, Qihong Chen, Shuling Hu, Haibo Qiu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3962348?pdf=render