Synthesis and Biological Evaluation of S-Substituted Perhalo-2-nitrobuta-1,3-dienes as Novel Xanthine Oxidase, Tyrosinase, Elastase, and Neuraminidase Inhibitors

S-substituted perhalo-2-nitrobuta-1,3-dienes 3a, b were synthesized by the reaction of polyhalo-2-nitrobuta-1,3-dienes 1a, b with allyl mercaptan. 1-(2,3-Dibromopropanethio)-4-bromo-1,3,4-trichloro-2-nitrobuta-1,3-diene 4 was obtained from the addition of bromine to S-substituted polyhalo-2-nitrobut...

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Bibliographic Details
Main Authors: Nihal Onul, Onur Ertik, Neşe Mermer, Refiye Yanardag
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2018/4386031