Utilization of microsatellites for the analysis of genomic alterations in colorectal cancers in Brazil

Two different pathogenetic mechanisms are proposed for colorectal cancers. One, the so-called "classic pathway", is the most common and depends on multiple additive mutational events (germline and/or somatic) in tumor suppressor genes and oncogenes, frequently involving chromosomal deletio...

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Bibliographic Details
Main Authors: A.K. Fuzikawa, L.A. Haddad, J.R. da-Cunha-Melo, G. Brasileiro-Filho, S.D.J. Pena
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 1997-08-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
p53
DCC
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000800001