Periostin deficiency increases bone damage and impairs injury response to fatigue loading in adult mice.

Bone damage removal and callus formation in response to fatigue loading are essential to prevent fractures. Periostin (Postn) is a matricellular protein that mediates adaptive response of cortical bone to loading. Whether and how periostin influences damage and the injury response to fatigue remains...

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Bibliographic Details
Main Authors: Nicolas Bonnet, Evelyne Gineyts, Patrick Ammann, Simon J Conway, Patrick Garnero, Serge Ferrari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3805534?pdf=render