Scaffold-free 3D bio-printed human liver tissue stably maintains metabolic functions useful for drug discovery

The liver plays a central role in metabolism. Although many studies have described in vitro liver models for drug discovery, to date, no model has been described that can stably maintain liver function. Here, we used a unique, scaffold-free 3D bio-printing technology to construct a small portion of...

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Bibliographic Details
Main Authors: Hideki Kizawa, Eri Nagao, Mitsuru Shimamura, Guangyuan Zhang, Hitoshi Torii
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
3D
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580817300596