Disruption of Adipokinetic Hormone Mediated Energy Homeostasis Has Subtle Effects on Physiology, Behavior and Lipid Status During Aging in Drosophila

Disruption of Adipokinetic Hormone Mediated Energy Homeostasis Has Subtle Effects on Physiology, Behavior and Lipid Status During Aging in Drosophila

The impact of disruption of adipokinetic hormone (AKH) signaling was studied during aging in Drosophila in a sexually dimorphic manner. A mutant (Akh1) producing a non-functional AKH peptide was compared with isogenized wild-type controls (w1118), and Akh-rescue line where AKH was ectopically expres...

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Bibliographic Details
Main Authors: Andrea Bednářová, Aleš Tomčala, Michaela Mochanová, Dalibor Kodrík, Natraj Krishnan
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Physiology
Subjects:
adipokinetic hormone
aging
AKH signaling
lipid status
senescence
energy homeostasis
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.00949/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.00949/full

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