Genomic Fabric Remodeling in Metastatic Clear Cell Renal Cell Carcinoma (ccRCC): A New Paradigm and Proposal for a Personalized Gene Therapy Approach

Genomic Fabric Remodeling in Metastatic Clear Cell Renal Cell Carcinoma (ccRCC): A New Paradigm and Proposal for a Personalized Gene Therapy Approach

Published transcriptomic data from surgically removed metastatic clear cell renal cell carcinoma samples were analyzed from the genomic fabric paradigm (GFP) perspective to identify the best targets for gene therapy. GFP considers the transcriptome as a multi-dimensional mathematical object constrai...

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Bibliographic Details
Main Authors: Dumitru A. Iacobas, Victoria E. Mgbemena, Sanda Iacobas, Kareena M. Menezes, Huichen Wang, Premkumar B. Saganti
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
<i>ALG13</i>
basal transcription factors
cell cycle
chemokine signaling
<i>FAM27C</i>
genomic medicine
Online Access:https://www.mdpi.com/2072-6694/12/12/3678

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