Sequencing of the Canine Cytochrome P450 CYP2C41 Gene and Genotyping of Its Polymorphic Occurrence in 36 Dog Breeds

Cytochrome P450 (CYP) drug metabolizing enzymes play an important role in efficient drug metabolism and elimination. Many CYPs are polymorphic and, thereby, drug metabolism can vary between individuals. In the case of canine CYP2C41, gene polymorphism was identified. However, as the first available...

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Bibliographic Details
Main Authors: Emre Karakus, Clarissa Prinzinger, Silke Leiting, Joachim Geyer
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Veterinary Science
Subjects:
dog
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2021.663175/full