Global migration and the changing distribution of sickle haemoglobin: a quantitative study of temporal trends between 1960 and 2000

Background: Changes in the geographical distribution of genetic disorders are often thought to happen slowly, especially when compared with infectious diseases. Whereas mutations, genetic drift, and natural selection take place over many generations, epidemics can spread through large populations w...

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Bibliographic Details
Main Authors: Dr. Frédéric B Piel, PhD, Andrew J Tatem, PhD, Zhuojie Huang, PhD, Prof. Sunetra Gupta, PhD, Prof. Thomas N Williams, MRCP, Prof. David J Weatherall, FRS
Format: Article
Language:English
Published: Elsevier 2014-02-01
Series:The Lancet Global Health
Online Access:http://www.sciencedirect.com/science/article/pii/S2214109X13701505