Thermoresponsive sol-gel improves ocular bioavailability of Dipivefrin hydrochloride and potentially reduces the elevated intraocular pressure in vivo
The present study involves the development of Dipivefrin hydrochloride (DV) containing Poloxamers (P407 and P188)-Carbopol-934 (CP) based thermoresponsive-gels for the management of elevated intraocular pressure (IOP). Optimal formulation was evaluated for gelation temperature (Tgel), physicochemica...
Main Authors: | Musaed Alkholief, Mohd Abul Kalam, Aliyah Almomen, Abdullah Alshememry, Aws Alshamsan |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-08-01
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Series: | Saudi Pharmaceutical Journal |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1319016420301523 |
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