Analgesic Activity of Acid-Sensing Ion Channel 3 (ASIС3) Inhibitors: Sea Anemones Peptides Ugr9-1 and APETx2 versus Low Molecular Weight Compounds

Analgesic Activity of Acid-Sensing Ion Channel 3 (ASIС3) Inhibitors: Sea Anemones Peptides Ugr9-1 and APETx2 versus Low Molecular Weight Compounds

Acid-sensing ion channel 3 (ASIC3) makes an important contribution to the development and maintenance of inflammatory and acid-induced pain. We compared different ASIC3 inhibitors (peptides from sea anemones (APETx2 and Ugr9-1) and nonpeptide molecules (sevanol and diclofenac)) in anti-inflammatory...

Full description

Bibliographic Details
Main Authors: Yaroslav A. Andreev, Dmitry I. Osmakov, Sergey G. Koshelev, Ekaterina E. Maleeva, Yulia A. Logashina, Victor A. Palikov, Yulia A. Palikova, Igor A. Dyachenko, Sergey A. Kozlov
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Marine Drugs
Subjects:
acid-sensing ion channel
animal models
pain relief
toxin
Ugr 9-1
APETx2
Online Access:https://www.mdpi.com/1660-3397/16/12/500

Internet

https://www.mdpi.com/1660-3397/16/12/500

Similar Items