Clinical Evaluation of Pathognomonic Salivary Protease Fingerprinting for Oral Disease Diagnosis

Clinical Evaluation of Pathognomonic Salivary Protease Fingerprinting for Oral Disease Diagnosis

Dental decay (Caries) and periodontal disease are globally prevalent diseases with significant clinical need for improved diagnosis. As mediators of dental disease-specific extracellular matrix degradation, proteases are promising analytes. We hypothesized that dysregulation of active proteases can...

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Bibliographic Details
Main Authors: Garrit Koller, Eva Schürholz, Thomas Ziebart, Andreas Neff, Roland Frankenberger, Jörg W. Bartsch
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Journal of Personalized Medicine
Subjects:
Oral Biomarkers
caries detection
real-time protease activities
metalloproteases
FRET-peptides
proteolysis
Online Access:https://www.mdpi.com/2075-4426/11/9/866

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https://www.mdpi.com/2075-4426/11/9/866

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