Genetic Predispositions of Glucocorticoid Resistance and Therapeutic Outcomes in Polymyalgia Rheumatica and Giant Cell Arteritis

Genetic Predispositions of Glucocorticoid Resistance and Therapeutic Outcomes in Polymyalgia Rheumatica and Giant Cell Arteritis

Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are closely related chronic inflammatory diseases. Glucocorticoids (GCs) are first-choice drugs for PMR and GCA, although some patients show poor responsiveness to the initial GC regimen or experience flares after GC tapering. To date, no v...

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Bibliographic Details
Main Authors: Tomas Smutny, Ivan Barvik, Tomas Veleta, Petr Pavek, Tomas Soukup
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Journal of Clinical Medicine
Subjects:
pharmacogenetics
glucocorticoid resistance
giant cell arteritis
polymyalgia rheumatica
Online Access:https://www.mdpi.com/2077-0383/8/5/582

Internet

https://www.mdpi.com/2077-0383/8/5/582

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