lncRNA CRNDE promotes the proliferation and metastasis by acting as sponge miR-539-5p to regulate POU2F1 expression in HCC

Abstract Background This article focuses on the roles and mechanism of lncRNA CRNDE on the progression of HCC. Methods We used qRT-PCR to detect the expression of lncRNA CRNDE in HCC cells, normal cells and clinical tissues. MTT assay, FCM analysis, Transwell migration and invasion assay were used t...

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Bibliographic Details
Main Authors: Zhixi Li, Gang Wu, Jie Li, Youyu Wang, Xueming Ju, Wenjun Jiang
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Cancer
Subjects:
HCC
Online Access:http://link.springer.com/article/10.1186/s12885-020-06771-y