The ratio 1660/1690 cm(-1) measured by infrared microspectroscopy is not specific of enzymatic collagen cross-links in bone tissue.
In postmenopausal osteoporosis, an impairment in enzymatic cross-links (ECL) occurs, leading in part to a decline in bone biomechanical properties. Biochemical methods by high performance liquid chromatography (HPLC) are currently used to measure ECL. Another method has been proposed, by Fourier Tra...
Main Authors: | Delphine Farlay, Marie-Eve Duclos, Evelyne Gineyts, Cindy Bertholon, Stéphanie Viguet-Carrin, Jayakrupakar Nallala, Ganesh D Sockalingum, Dominique Bertrand, Thierry Roger, Daniel J Hartmann, Roland Chapurlat, Georges Boivin |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22194900/?tool=EBI |
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