Mathematical Modeling as a Tool to Describe and Optimize Heterologous Protein Production by Yeast Cells in Aerated Fed-Batch Reactor
In this work, two recombinant yeast strains, the prototrophic non-conventional Zygosaccharomyces bailii [pZ3KlIL-1ß] and the auxotrophic Saccharomyces cerevisiae BY4741[PIR4-IL1ß], both producing human interleukin-1ß, have been cultured in aerated fed-batch using glucose as limiting substrate. A mat...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
AIDIC Servizi S.r.l.
2012-06-01
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| Series: | Chemical Engineering Transactions |
| Online Access: | https://www.cetjournal.it/index.php/cet/article/view/7329 |