High-throughput validation of ceRNA regulatory networks

High-throughput validation of ceRNA regulatory networks

Abstract Background MicroRNAs (miRNAs) play multiple roles in tumor biology. Interestingly, reports from multiple groups suggest that miRNA targets may be coupled through competitive stoichiometric sequestration. Specifically, computational models predicted and experimental assays confirmed that miR...

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Bibliographic Details
Main Authors: Hua-Sheng Chiu, María Rodríguez Martínez, Mukesh Bansal, Aravind Subramanian, Todd R. Golub, Xuerui Yang, Pavel Sumazin, Andrea Califano
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Genomics
Subjects:
ceRNA
microRNA
LINCS
PRAD
BRCA
Online Access:http://link.springer.com/article/10.1186/s12864-017-3790-7

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http://link.springer.com/article/10.1186/s12864-017-3790-7

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