Detecting overlapping protein complexes in weighted PPI network based on overlay network chain in quotient space

Abstract Background Protein complexes are the cornerstones of many biological processes and gather them to form various types of molecular machinery that perform a vast array of biological functions. In fact, a protein may belong to multiple protein complexes. Most existing protein complex detection...

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Bibliographic Details
Main Authors: Jie Zhao, Xiujuan Lei
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-019-3256-9