Antifungal and Antibacterial Metabolites from a French Poplar Type Propolis
During this study, the in vitro antifungal and antibacterial activities of different extracts (aqueous and organic) obtained from a French propolis batch were evaluated. Antifungal activity was evaluated by broth microdilution on three pathogenic strains: Candida albicans, C. glabrata, and Aspergill...
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Series: | Evidence-Based Complementary and Alternative Medicine |
Online Access: | http://dx.doi.org/10.1155/2015/319240 |
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doaj-c5cccab202274cbea9a71bfb3ac887f22020-11-25T00:22:52ZengHindawi LimitedEvidence-Based Complementary and Alternative Medicine1741-427X1741-42882015-01-01201510.1155/2015/319240319240Antifungal and Antibacterial Metabolites from a French Poplar Type PropolisSéverine Boisard0Anne-Marie Le Ray1Anne Landreau2Marie Kempf3Viviane Cassisa4Catherine Flurin5Pascal Richomme6EA 921 SONAS/SFR 4207 QUASAV, Université d’Angers, 16 boulevard Daviers, 49045 Angers Cedex 01, FranceEA 921 SONAS/SFR 4207 QUASAV, Université d’Angers, 16 boulevard Daviers, 49045 Angers Cedex 01, FranceEA 921 SONAS/SFR 4207 QUASAV, Université d’Angers, 16 boulevard Daviers, 49045 Angers Cedex 01, FranceLaboratoire de Bactériologie-Hygiène, Centre Hospitalier Universitaire, 4 rue Larrey, 49933 Angers Cedex 09, FranceLaboratoire de Bactériologie-Hygiène, Centre Hospitalier Universitaire, 4 rue Larrey, 49933 Angers Cedex 09, FranceBallot-Flurin Apiculteurs-Abeilles Santé, 75 place Lagardère, 65700 Maubourguet, FranceEA 921 SONAS/SFR 4207 QUASAV, Université d’Angers, 16 boulevard Daviers, 49045 Angers Cedex 01, FranceDuring this study, the in vitro antifungal and antibacterial activities of different extracts (aqueous and organic) obtained from a French propolis batch were evaluated. Antifungal activity was evaluated by broth microdilution on three pathogenic strains: Candida albicans, C. glabrata, and Aspergillus fumigatus. Antibacterial activity was assayed using agar dilution method on 36 Gram-negative and Gram-positive strains including Staphylococcus aureus. Organic extracts showed a significant antifungal activity against C. albicans and C. glabrata (MIC80 between 16 and 31 µg/mL) but only a weak activity towards A. fumigatus (MIC80 = 250 µg/mL). DCM based extracts exhibited a selective Gram-positive antibacterial activity, especially against S. aureus (SA) and several of its methicillin-resistant (MRSA) and methicillin-susceptible (MSSA) strains (MIC100 30–97 µg/mL). A new and active derivative of catechin was also identified whereas a synergistic antimicrobial effect was noticed during this study.http://dx.doi.org/10.1155/2015/319240 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Séverine Boisard Anne-Marie Le Ray Anne Landreau Marie Kempf Viviane Cassisa Catherine Flurin Pascal Richomme |
spellingShingle |
Séverine Boisard Anne-Marie Le Ray Anne Landreau Marie Kempf Viviane Cassisa Catherine Flurin Pascal Richomme Antifungal and Antibacterial Metabolites from a French Poplar Type Propolis Evidence-Based Complementary and Alternative Medicine |
author_facet |
Séverine Boisard Anne-Marie Le Ray Anne Landreau Marie Kempf Viviane Cassisa Catherine Flurin Pascal Richomme |
author_sort |
Séverine Boisard |
title |
Antifungal and Antibacterial Metabolites from a French Poplar Type Propolis |
title_short |
Antifungal and Antibacterial Metabolites from a French Poplar Type Propolis |
title_full |
Antifungal and Antibacterial Metabolites from a French Poplar Type Propolis |
title_fullStr |
Antifungal and Antibacterial Metabolites from a French Poplar Type Propolis |
title_full_unstemmed |
Antifungal and Antibacterial Metabolites from a French Poplar Type Propolis |
title_sort |
antifungal and antibacterial metabolites from a french poplar type propolis |
publisher |
Hindawi Limited |
series |
Evidence-Based Complementary and Alternative Medicine |
issn |
1741-427X 1741-4288 |
publishDate |
2015-01-01 |
description |
During this study, the in vitro antifungal and antibacterial activities of different extracts (aqueous and organic) obtained from a French propolis batch were evaluated. Antifungal activity was evaluated by broth microdilution on three pathogenic strains: Candida albicans, C. glabrata, and Aspergillus fumigatus. Antibacterial activity was assayed using agar dilution method on 36 Gram-negative and Gram-positive strains including Staphylococcus aureus. Organic extracts showed a significant antifungal activity against C. albicans and C. glabrata (MIC80 between 16 and 31 µg/mL) but only a weak activity towards A. fumigatus (MIC80 = 250 µg/mL). DCM based extracts exhibited a selective Gram-positive antibacterial activity, especially against S. aureus (SA) and several of its methicillin-resistant (MRSA) and methicillin-susceptible (MSSA) strains (MIC100 30–97 µg/mL). A new and active derivative of catechin was also identified whereas a synergistic antimicrobial effect was noticed during this study. |
url |
http://dx.doi.org/10.1155/2015/319240 |
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