A dual role for microglia in promoting tissue inhibitor of metalloproteinase (TIMP) expression in glial cells in response to neuroinflammatory stimuli

<p>Abstract</p> <p>Background</p> <p>By neutralizing the effect of the matrix metalloproteinases (MMPs), the tissue inhibitors of matrix metalloproteinases (TIMPs) play a critical role in maintaining tissue proteolysis in balance. As the major reactive glial cell types...

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Bibliographic Details
Main Authors: Milner Richard, Crocker Stephen J, Welser-Alves Jennifer V
Format: Article
Language:English
Published: BMC 2011-06-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/8/1/61