Sample size calculation for estimating key epidemiological parameters using serological data and mathematical modelling

Abstract Background Our work was motivated by the need to, given serum availability and/or financial resources, decide on which samples to test in a serum bank for different pathogens. Simulation-based sample size calculations were performed to determine the age-based sampling structures and optimal...

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Bibliographic Details
Main Authors: Stéphanie Blaizot, Sereina A. Herzog, Steven Abrams, Heidi Theeten, Amber Litzroth, Niel Hens
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12874-019-0692-1