Trichuris muris infection drives cell-intrinsic IL4R alpha independent colonic RELMα+ macrophages.

Trichuris muris infection drives cell-intrinsic IL4R alpha independent colonic RELMα+ macrophages.

The intestinal nematode parasite Trichuris muris dwells in the caecum and proximal colon driving an acute resolving intestinal inflammation dominated by the presence of macrophages. Notably, these macrophages are characterised by their expression of RELMα during the resolution phase of the infection...

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Bibliographic Details
Main Authors: Ruth Forman, Larisa Logunova, Hannah Smith, Kelly Wemyss, Iris Mair, Louis Boon, Judith E Allen, Werner Muller, Joanne L Pennock, Kathryn J Else
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009768

Internet

https://doi.org/10.1371/journal.ppat.1009768

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