P2Y2R Signaling Is Involved in the Onset of Glomerulonephritis

P2Y2R Signaling Is Involved in the Onset of Glomerulonephritis

Endogenously released adenosine-5’-triphosphate (ATP) is a key regulator of physiological function and inflammatory responses in the kidney. Genetic or pharmacological inhibition of purinergic receptors has been linked to attenuation of inflammatory disorders and hence constitutes promising new aven...

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Bibliographic Details
Main Authors: Laura Rennert, Stefan Zschiedrich, Lukas Sandner, Björn Hartleben, Sanja Cicko, Cemil Korcan Ayata, Charlotte Meyer, Andreas Zech, Robert Zeiser, Tobias B. Huber, Marco Idzko, Florian Grahammer
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
glomerulonephritis
leukocytes
purinergic receptors
P2Y2
adenosine-5’-triphosphate
animal model
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01589/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01589/full

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