LC3-Associated Phagocytosis (LAP): A Potentially Influential Mediator of Efferocytosis-Related Tumor Progression and Aggressiveness

LC3-Associated Phagocytosis (LAP): A Potentially Influential Mediator of Efferocytosis-Related Tumor Progression and Aggressiveness

One aim of cancer therapies is to induce apoptosis of tumor cells. Efficient removal of the apoptotic cells requires coordinated efforts between the processes of efferocytosis and LC3-associated phagocytosis (LAP). However, this activity has also been shown to produce anti-inflammatory and immunosup...

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Bibliographic Details
Main Authors: Patrick F. Asare, Eugene Roscioli, Plinio R. Hurtado, Hai B. Tran, Chui Yan Mah, Sandra Hodge
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Oncology
Subjects:
efferocytosis
tumor cell apoptosis
LAP
tumor immune response
M2 macrophage activation
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01298/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.01298/full

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