Trends in Laboratory Diagnostic Methods in Periodontology

• Main Authors: Beáta Bolerázska, Mária Mareková, Neda Markovská
• Format: Article
• Language: English
• Published: Karolinum Press 2016-04-01
• Series: Acta Medica
• Subjects: Periodontitis; Diagnosis; Biomarkers; Saliva; Gingival crevicular fluid; Point-of care testing; Markers of bone remodelling

This work presents a summary of current knowledge on the laboratory diagnosis of periodontitis. It focuses on the theoretical foundations and is supplemented with new knowledge. It subsequently describes specifically the laboratory diagnosis methods of periodontitis: the protein expression of inflammation, oral microbiology and molecular diagnostics. Periodontitis is a serious disease worldwide and its confirmed association with systemic diseases means its severity is increasing. Its laboratory diagnosis has the potential to rise to the level of clinical and diagnostic imaging. The transfer of diagnostic methods from laboratory to clinical use is increasingly used in the prevention and monitoring of the exacerbation and treatment of periodontal disease, as well as of its impact on systemic disease.