Commonly Occurring Cell Subsets in High-Grade Serous Ovarian Tumors Identified by Single-Cell Mass Cytometry

Commonly Occurring Cell Subsets in High-Grade Serous Ovarian Tumors Identified by Single-Cell Mass Cytometry

Summary: We have performed an in-depth single-cell phenotypic characterization of high-grade serous ovarian cancer (HGSOC) by multiparametric mass cytometry (CyTOF). Using a CyTOF antibody panel to interrogate features of HGSOC biology, combined with unsupervised computational analysis, we identifie...

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Bibliographic Details
Main Authors: Veronica D. Gonzalez, Nikolay Samusik, Tiffany J. Chen, Erica S. Savig, Nima Aghaeepour, David A. Quigley, Ying-Wen Huang, Valeria Giangarrà, Alexander D. Borowsky, Neil E. Hubbard, Shih-Yu Chen, Guojun Han, Alan Ashworth, Thomas J. Kipps, Jonathan S. Berek, Garry P. Nolan, Wendy J. Fantl
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Cell Reports
Subjects:
high grade serious ovarian cancer
single cell
mass cytometry
CyTOF
hierarchical clustering
phenotypic characterization
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718301025

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http://www.sciencedirect.com/science/article/pii/S2211124718301025

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