A Proinflammatory Immune Response Might Determine Toxoplasma gondii Vertical Transmission and Severity of Clinical Features in Congenitally Infected Newborns

A Proinflammatory Immune Response Might Determine Toxoplasma gondii Vertical Transmission and Severity of Clinical Features in Congenitally Infected Newborns

Toxoplasma gondii is the etiological agent of toxoplasmosis. Mother-to-child transmission of this parasite can occur during pregnancy. Newborns with congenital toxoplasmosis may develop central nervous system impairment, with severity ranging from subclinical manifestations to death. A proinflammato...

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Bibliographic Details
Main Authors: Fernando Gómez-Chávez, Irma Cañedo-Solares, Luz Belinda Ortiz-Alegría, Yevel Flores-García, Ricardo Figueroa-Damián, Héctor Luna-Pastén, Valeria Gómez-Toscano, Carlos López-Candiani, G. Emmanuel Arce-Estrada, Christian A. Bonilla-Ríos, Juan Carlos Mora-González, Ricardo García-Ruiz, Dolores Correa
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Immunology
Subjects:
Toxoplasma gondii
immune response
human congenital toxoplasmosis
vertical transmission
TGF-β1
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00390/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00390/full

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